Wild Rue Seeds-Esphand Esfan is an aromatic seed commonly used to create incense and is burned with other grains and roots to create different aromas. 

Regarding the Benefits of Burning Esphand as an Incense:

Sayyidina Zayd b. 'Ali (as) [Zayn al-‘Abidin, the fourth Imam (d.122/740)] who attributed it to his forefathers, peace be upon them, that [one of them] said:

"The Messenger of Allah, blessings of Allah on him and his family, said: 'The wild rue (al-harmal) does not grow a tree, or a leaf, or a fruit, but that it has an angel in charge of it until it reaches the one who comes to it, or until it becomes debris. In its root and branches is a secret, and in its seed is healing from seventy-two illnesses. So treat yourselves with it and with frankincense.'"

From Abu' Abd Allah al-Sadiq, peace be upon him that he was asked about wild rue and storax. He said: "As for wild rue, neither its root in the earth nor its branch in the sky is shaken without an angel in charge of it until it becomes debris and becomes what it becomes. For Satan avoids seventy houses before the house it is, and it is a healing for seventy illnesses, the least of which is leprosy. So do not be heedless of it."

Du’a of Burning Espand, Harmal (Wild Rue)
 
اسپند، بلا بند
به حق شاه نقشبند
چشم هيش، چشم خيش
چشم آدم بد انديش
بسوزد در آتش تيز
 
Espand, balaa band 
Ba haqi Shah e Naqshband
Chashmi haysh, chashmi khaysh 
chashmi adam e bad andeysh
Besozad dar atashi teyz

O’ Espand, block the evil eye and hardship,
For the sake of Shah Bahauddin Naqshband (Q),
May the eyes of the one who wants to harm, the eyes of the relatives,
and the eyes of the people who have bad intentions, burn in this blazing fire
 Mawlana Shah Naqshbandi